Description
Please be aware that currently the GPL-TOX Profile has been experiencing supply chain and technical issues, which are causing ongoing delays with the completion of this test.
To prevent delays, GPL will report 14 out of the 19 analytes, temporarily until the other 5 reagents can be restored.
All urine samples will remain stable in the GPL freezers, testing samples will begin immediately and will be processed in the order received, you should expect first your test results in the next 2-3 weeks. The GPL-TOX Profile remains the only test affected by these issues. While GPL expect to have all markers back in operation, we cannot provide a date at this time.
You will continue to see the five analytes listed below on your GPL-TOX Profile report, with no result reported.
• 3 - 3MHA (11% historical positivity)
• 9 - HEMA (6% historical positivity)
• 12 - NAE (13% historical positivity)
• 13 - NADB (1% historical positivity)
• 14 - DMP (19% historical positivity)
In most instances other analytes on this test may provide equivalent insight into clinical concerns related to possible toxic exposures and clinical manifestations.
The GPL-TOX screens for 172 different environmental pollutants using 18 different metabolites from a single urine sample including organophosphate pesticides, phthalates, benzene, xylene, vinyl chloride, pyrethroid, insecticides, acrylamide, perchlorate, diphenyl phosphate, ethylene oxide, acrylonitrile and more. The profile also includes Tiglylglycine (TG), a marker for mitochondrial disorders resulting from mutations of mitochondrial DNA. GPL-TOX test is an important tool for assessing exposure to common environmental toxins.
Methodology
Measured by a combination of gas or liquid chromatography.
When should I use
Chronic illnesses, heart disease, chronic fatigue syndrome, chemical sensitivity, autism spectrum disorders, ADD/ADHD, autoimmune disorders, Parkinson’s disease, and Alzheimer’s disease.
Other Details
Alternatively consider GPL01 ENVIROTox Complete Panel, a cost-effective option that includes:
OAT, GPL-Tox, Mycotox and Glyphosate.
We understand that there is some discussion and no real agreement regarding challenging with glutathione before urine toxin testing. We don’t recommend this however it is a clinical decision that you may make for yourself.
However, Robyn Puglia, Clinical Support Specialist, suggests considering the following collection schedule to encourage mobilisation and elimination of toxins via urine:
The evening before the sample collection, immediately before going to bed:
First, empty the bladder, then perform full body dry body brushing followed by a hot bath with 4 cups of Epsom salts.
Then collect any urine passed from the time of getting out of the bath during the night and the first-morning void and create the sample out of the total urine collected.
