TSH receptor antibodies (TRAb) are antibodies that develop when a person’s immune system mistakenly targets the thyroid gland or thyroid proteins, leading to chronic inflammation of the thyroid (thyroiditis), tissue damage, and/or disruption of thyroid function. They are heterogeneous and may either mimic the action of TSH and cause hyperthyroidism or alternatively, antagonise the action of TSH and cause hypothyroidism.
When should I use
TSH receptor antibody test that is often used to investigate hyperthyroidism (Graves' disease) or to monitor the effectiveness of anti-thyroid treatment. May also be useful to determine route cause of hypothyroidism
This is an ADD-ON test to any BP Panel. TRAb is included in BP005 Thyroid Advanced