Description
TSH receptor antibodies (TRAb) are antibodies that develop when a person’s immune system mistakenly targets the thyroid gland or thyroid proteins, leading to chronic inflammation of the thyroid (thyroiditis), tissue damage, and/or disruption of thyroid function. They are heterogeneous and may either mimic the action of TSH and cause hyperthyroidism or alternatively, antagonise the action of TSH and cause hypothyroidism.
Methodology
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When should I use
TSH receptor antibody test that is often used to investigate hyperthyroidism (Graves' disease) or to monitor the effectiveness of anti-thyroid treatment. May also be useful to determine route cause of hypothyroidism
Other Details
This is an ADD-ON test to any BP Panel. TRAb is included in BP005 Thyroid Advanced
