ASSESSES 190 FOODS
Includes a wide range of foods, common in the Western, Asian, and Mediterranean diets. We have added a hemp allergy marker because it is very common now as a food source or as medical CBD. We are able to run the IgG Food MAP on both serum and dried blood spot samples.
SUPERIOR SENSITIVITY AND ACCURACY.
GPL’s xMAP® immunoassay with fluorescence readout has proven to be even more sensitive than ELISA tests. The IgG Food MAP test detects all food antibodies with greater precision than ELISA tests thanks to the superior technology GPL developed for the test.
GREATER RELIABILITY OF RESULTS
In the multiplexed bead-based immunoassay, food antigenic proteins are first covalently bound to beads. The beads are mixed with the patient’s sample where bead-bound antigens capture the specific IgG antibodies present in the sample. The food-specific IgG antibody level of each sample is detected with a fluorescent-labeled antibody against IgG. Every reaction with a patient sample also contains control beads to ensure accurate results. The fluorescent signal is measured using an xMAP® analyzer. The amount of food-specific antibody detected per allergen specific bead is directly proportional to the fluorescent signals. The higher the fluorescence, the more specific IgG antibodies are present in the sample. Once test results are available for review, GPL's Quality Assurance (QA) team carefully verifies that quality control measures are within instrument and assay specifications.
Antigen-specific IgG antibodies are captured on multiplexed magnetic beads, using xMAP® (Multiple Analyte Profiling) technology. The xMAP® bead-based immunoassay allows for the simultaneous detection of IgG antibodies to all 190 foods in two single test wells, reducing sample volume requirements and reagents while increasing sensitivity and specificity as compared to traditional plate-based ELISA tests. The upgraded immunoassay is cost and time effective, easy to perform and reproducible. GPL have now fully automated all steps of our testing processes, leading to even better precision.
The xMAP® bead-based immunoassay is environmentally friendly, reducing plastic pollution. In the ELISA, a panel for 190 foods would require 190 wells (2 plates) per sample. In contrast, the beadbased platform only requires two wells per sample. In other words, the bead-based immunoassay would use just one plastic microtiter plate for testing 48 samples, while the ELISA would use 96 plates to test the same number of samples.