Description
Mycotoxins (toxins from mould) are some of the most prevalent toxins in the environment. Mycotoxins are metabolites produced by fungi like mould, which can infest buildings, vehicles, and foodstuffs. Most mycotoxin exposures in North America, Europe, and Australia are through airborne exposure. Food may be a major source of mycotoxins in third-world nations that lack government inspection of foods, especially the grains such as rice, corn, wheat, rye, and barley. Many grains that are harvested have been found to be contaminated with mycotoxins but little of such harvests are discarded and are frequently sold for animal feeds such as dog food or feed for cows, pigs, chickens, turkeys, and horses.
Fungi can grow on almost any surface, especially if the environment is warm and wet. Inner wall materials of buildings, wallpaper, fibre glass insulation, ceiling tiles, and gypsum support are all good surfaces for fungi to colonize. These fungi then release mycotoxins into the environment causing symptoms of many different chronic diseases.
This test is combined with Great Plains organic acid test includes 76 urinary metabolites that provide a comprehensive snapshot of a patient’s overall health as the initial screening test and is useful for discovering underlying causes for chronic illness.
Includes biomarkers for
Intestinal Microbial Overgrowth
Oxalate Metabolites
Glycolytic Cycle Metabolites
Mitochondrial Makers (Kreb Cycle)
Neurotransmitter Metabolites
Folate Metabolism
Ketone and Fatty Acid Oxidation
Nutritional Markers
Indicators of Detoxification
Amino Acid Metabolites
Organic acids are chemical compounds excreted in the urine that are products of metabolism. Metabolism is the sum of chemical reactions in living beings by which the body builds new molecules and breaks down molecules to eliminate waste products and produce energy.
Organic acids are commonly analysed in urine because they are not extensively reabsorbed in the kidney tubules after glomerular filtration. Thus, organic acids in urine are often present at 100 times their concentration in the blood serum and thus are more readily detected in urine. This is why organic acids are rarely tested in blood or serum.
Methodology
Their primary goals for this test were to design a test that would be more sensitive and accurate as well as more affordable than those currently on the market. They were able to achieve these goals with state-of-the-art liquid chromatography-mass spectrometry (LC-MS/MS) technology. Using this technology, they have a very sensitive test, which is important because mycotoxins can cause serious health issues even in small quantities. Other mycotoxin testing uses ELISA technology, which relies on antibodies. In addition, all the results from urine tests performed at The Great Plains Laboratory are corrected for differences in fluid intake using the technique called creatinine correction. Failure to use creatinine correction can lead to a thirty-fold variation in the concentration of the mycotoxins when there is variation in fluid intake. Utilization of LC-MS/MS technology gives us a precise identification of all our analytes, which prevents having false-positive errors. For many of their compounds they can detect amounts in the parts per trillion (ppt) which is about 100-fold better than any other test currently available.
When should I use
Diseases and symptoms linked to mycotoxin exposure include fever, pneumonia-like symptoms, heart disease, rheumatic disease, asthma, sinusitis, cancer, memory loss, vision loss, chronic fatigue, skin rashes, depression, ADHD, anxiety, and liver damage.
Other Details
MOAT CMI32 GPL TOX + OAT CMI43 ENVIROtox Complete Panel GPL01 OAT CMI30
