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Providing you with simple, easy access to world-leading laboratories that deliver the broadest range of wellness focussed diagnostic testing services.
For health professionals and patients across the UK and around the world.

Precision Point Diagnostics - PD005

Advanced Intestinal Barrier Assessment

Digestive Health Blood (Venous) Turn Around Time: 14 Days
Recommended: Contact practitioner before placing order
Turn Around Time: 14 Days

Description

Precision Point Diagnostics’ Advanced Intestinal Barrier Assessment takes a deep dive into intestinal barrier function. Using a collection of innovative biomarkers, this test helps clinicians determine if their patients have intestinal permeability, or “leaky gut.” Intestinal permeability has been suggested as a root cause of autoimmune diseases, systemic inflammation, and food sensitivities. Healing the gut barrier is so pivotal for resolving chronic disease that if it isn’t addressed, other treatments will have little to no effect.
The Advanced Intestinal Barrier Assessment stands out for its unique, clinically relevant markers which tell a complex story about gut barrier health. Histamine and diamine oxidase (DAO) give information about histamine balance and gut mucosal health. Plasma Zonulin is a well-documented marker of intestinal tight junctions and is the preferred specimen for assessment. Lipopolysaccharides (LPS) are endotoxins produced by gram-negative bacteria. LPS antibodies give information about inflammation and intestinal permeability.

Methodology

ELISA

When should I use

If the patient is taking steroids, immunosuppressant medications or other medications that may suppress antibodies please check if it is appropriate for them to test.

Precision Point Diagnostic’s Advanced Intestinal Barrier Assessment allows you to identify imbalances associated with increased intestinal permeability, often referred to as “leaky gut”. The results can help guide treatment protocols and progress can then be monitored over time.

Patients with allergies, food sensitivities, digestive symptoms, headache, cognitive decline, depression, and more can benefit from this test.

Other Details

Other tests to consider:
Precision Point Diagnostics P88 Dietary Antigen Test (serum or finger prick). This test identifies IgE, IgG4, IgG and Complement reactions to 88 commonly eaten foods.
  • DAO: Histamine Ratio
  • Diamine Oxidase (DAO)
  • Histamine
  • LPS IgA
  • LPS IgG
  • LPS IgM
  • Zonulin

View Details

Description

Precision Point Diagnostics’ Advanced Intestinal Barrier Assessment takes a deep dive into intestinal barrier function. Using a collection of innovative biomarkers, this test helps clinicians determine if their patients have intestinal permeability, or “leaky gut.” Intestinal permeability has been suggested as a root cause of autoimmune diseases, systemic inflammation, and food sensitivities. Healing the gut barrier is so pivotal for resolving chronic disease that if it isn’t addressed, other treatments will have little to no effect.
The Advanced Intestinal Barrier Assessment stands out for its unique, clinically relevant markers which tell a complex story about gut barrier health. Histamine and diamine oxidase (DAO) give information about histamine balance and gut mucosal health. Plasma Zonulin is a well-documented marker of intestinal tight junctions and is the preferred specimen for assessment. Lipopolysaccharides (LPS) are endotoxins produced by gram-negative bacteria. LPS antibodies give information about inflammation and intestinal permeability.

Methodology

ELISA

When should I use

If the patient is taking steroids, immunosuppressant medications or other medications that may suppress antibodies please check if it is appropriate for them to test.

Precision Point Diagnostic’s Advanced Intestinal Barrier Assessment allows you to identify imbalances associated with increased intestinal permeability, often referred to as “leaky gut”. The results can help guide treatment protocols and progress can then be monitored over time.

Patients with allergies, food sensitivities, digestive symptoms, headache, cognitive decline, depression, and more can benefit from this test.

Other Details

Other tests to consider:
Precision Point Diagnostics P88 Dietary Antigen Test (serum or finger prick). This test identifies IgE, IgG4, IgG and Complement reactions to 88 commonly eaten foods.

View Analytes

  • DAO: Histamine Ratio
  • Diamine Oxidase (DAO)
  • Histamine
  • LPS IgA
  • LPS IgG
  • LPS IgM
  • Zonulin

View Instructions

English