Comprehensive Adrenal Stress with CAR

 The cortisol awakening response is the natural rise in cortisol that is seen 30 to 40 minutes after awakening followed by a noticeable drop by 60 minutes. CAR can be utilized as a biomarker for assessment of the HPA axis function in routine clinical practice. The CAR is influenced by overall HPA reactivity, as well as a person’s anticipation of stress.  In this profile, the CAR is combined with 3 other measures of cortisol at timed intervals throughout the day, one measure of DHEA, and secretory IgA (sIgA).  SIgA primarily provides insight into the body’s stress response and mucosal immunity status.